Latest Publications

Farag A, Samir H, Koung Ngeun S, Kaneda M, Hendawy H, Takahashi K, Tanaka R. Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis. Front Cell Dev Biol. 13:1604605. 2025.

Elhaieg A, Farag A, Koung Ngeun S, Kaneda M, Yokoi A, Mandour AS, Tanaka R Therapeutic Potential of Local and Systemic Adipose-Derived Mesenchymal Stem Cell Injections in a Rat Model of Experimental Periodontitis: Implications for Cardiac Function. Int J Mol Sci. 26(9). 2025.

Helal May, Farag A, Elbadawy M, Usui T, Sasaki K, Tanaka R, Mandour AS. Early Detection of Lapatinib-Induced Cardiotoxicity in Dogs Using Intraventricular Pressure Gradients and Two-Dimensional Speckle-Tracking Echocardiography. Pakistan Veterinary Journal. 45(2):751-758. 2025.

Zhao X, Tanaka R, Mandour AS, Shimada K, Hamabe L. Remote vital sensing in clinical veterinary medicine: A comprehensive review of recent advances, accomplishments, challenges, and future perspectives. Animals. 15(7):1033. 2025.

Xu T, Mandour AS, Shimada K, Hamabe L, Tanaka R. A comprehensive overview of respiratory compliance in dogs under general anesthesia: Clinical factors and future perspectives. Animals. 15(5):746. 2025.

Lee, Y. H., Saio, T., Watabe, M., Matsusaki, M., Kanemura, S., Lin, Y., Mannen, T., Kuramochi, T., Kamada, Y., Iuchi, K., Tajiri, M., Suzuki, K., Li, Y., Heo, Y., Ishii, K., Arai, K., Ban, K., Hashimoto, M., Oshita, S., Ninagawa, S., Hattori, Y., Kumeta, H., Takeuchi, A., Kajimoto, S., Abe, H., Mori, E., Muraoka, T., Nakabayashi, T., Akashi, S., Okiyoneda, T., Vendruscolo, M., Inaba, K., and Okumura, M. Ca²⁺-driven PDIA6 biomolecular condensation ensures proinsulin folding. Nature Cell Biology (Nat. Cell Biol.), 2025, https://doi.org/10.1038/s41556-025-01794-8.

Mori, K., Kuramochi, T., Matsusaki, M., Hashiguchi, Y., Okumura, M., Saio, T., Furukawa, Y., Arai, K., and Muraoka, T. Metal-responsive up-regulation of bifunctional disulfides for suppressing protein misfolding and promoting oxidative folding. Angewandte Chemie International Edition (Angew. Chem. Int. Ed.) 64, e202502187, 2025.

Yaguchi, A., Uchida, N., Miura, D., Watanabe, G., Hiramatsu, H., Ajioka, I., Matsubara, T., Sato, T., Enkhzaya, C., Itani, S., Saito, T., and Muraoka, T. A photoresponsive hybrid of viruses and supramolecular peptide fibers for multidimensional control of patterning and infection. Angewandte Chemie International Edition (Angew. Chem. Int. Ed.) 64, e202508528, 2025.

Hoshikawa, Y., Shirota, N., Tsugawa, H., Kimura, S., Matsuyama, A., Yashiroda, Y., Kakeya, H., Arita, M., Fenical, W., Yoshida, M., and Nishimura, S. Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast. Proceedings of the National Academy of Sciences of the United States of America (Proc. Natl. Acad. Sci. U.S.A.) 122, e2422126122, 2025.

Damiani, T., Jarmusch, A., Aron, A., Petras, D., Phelan, V., Zhao, H., Bittremieux, W., Acharya, D., Ahmed, M., Bauermeister, A., Bertin, M., Boudreau, P., Borges, R., Bowen, B., Brown, C., Chagas, F., Clevenger, K., Correia, M., Crandall, W., Crüsemann, M., Fahy, E., Fiehn, O., Garg, N., Gerwick, W., Gilbert, J., Globisch, D., Gomes, P. W. P., Heuckeroth, S., James, C., Jarmusch, S., Kakhkhorov, S., Kang, K. B., Kessler, N., Kersten, R., Kim, H. W., Kirk, R., Kohlbacher, O., Kontou, E., Liu, K., Lizama-Chamu, I., Luu, G., Luzzatto Knaan, T., Mannochio-Russo, H., Marty, M., Matsuzawa, Y., McAvoy, A., McCall, L.-I., Mohamed, O., Nahor, O., Neuweger, H., Niedermeyer, T., Nishida, K., Northen, T., Overdahl, K., Rainer, J., Reher, R., Rodriguez, E., Sachsenberg, T., Sanchez, L., Schmid, R., Stevens, C., Subramaniam, S., Tian, Z., Tripathi, A., Tsugawa, H., van der Hooft, J., Vicini, A., Walter, A., Weber, T., Xiong, Q., Xu, T., Pluskal, T., Dorrestein, P., and Wang, M. A universal language for finding mass spectrometry data patterns. Nature Methods (Nat. Methods) 22, 1247–1254, 2025. https://doi.org/10.1038/s41592-025-02660-z

Theodorou, C., de-Prado-Parralejo, V., Xu, D., Todoroki, Y., Svenningsen, L., Mori, T., Crocoll, C., Yokota Hirai, M., Tsugawa, H., Nour-Eldin, H. H., and Halkier, B. A. Development of plant extracts as substrates for untargeted transporter substrate identification in Xenopus oocytes. Frontiers in Plant Science (Front. Plant Sci.) 16, 1640426, 2025.

Ishihara, T., Tsugawa, H., Iwanami, S., Chang, J.-C., Minoda, A., and Arita, M. Transcriptomic and lipidomic analysis of aging-associated inflammatory signature in mouse liver. Inflammation and Regeneration (Inflamm. Regen.) 45, 13, 2025.

Koelmel, J. P., Lin, E. Z., Chang, P., Johnson, E., Stelben, P., Liu, S., Nishida, K., Tsugawa, H., Lin, A., Newton, S., Casey, J. S., Nikiforov, V., Roberts, D., Aksenov, A., Okeme, J., Metayer, C., Vieira, V. M., Manz, K. E., Braun, J. M., Pennell, K. D., Robey, N. M., Bangma, J., Strynar, M., Townsend, T. G., Bowden, J. A., and Godri Pollitt, K. J. Shedding light on PFAS dark matter using a novel GC-HRMS approach. Environmental Science & Technology (Environ. Sci. Technol.) 59, 25296–25308, 2025.

Neumann, S., Meier, R., Wenk, M., Elapavalore, A., Nishioka, T., Schulze, T., Stravs, M., Tsugawa, H., Matsuda, F., and Schymanski, E. L. MassBank: an open and FAIR mass spectral data resource. Nucleic Acids Research (Nucleic Acids Res.) 54, D601–D606, 2026.

Kosaka, S., Fukushima, J., Takeuchi, N., Miyamoto, N., de Campo, L., Kawano, R., and Nishimura, T. Self-assembled block copolymer domains as macromolecular ion transport systems in biological membranes.Chemical Science (Chem. Sci.), 16, 16522–16533, 2025.

Higashi, R., Shibayama, I., Ji, J., Ren, T., Kiiski, I., Takeuchi, N., and Kawano, R. Molecular diagnostics for infectious disease and cancer based on glass capillary nanopore sensing. Current Opinion in Biotechnology (Curr. Opin. Biotechnol.), 97, 103394, 2026.

Yuki Takechi‑Haraya, Takashi Ohgita, Akiko Usui, Kazuchika Nishitsuji, Kenji Uchimura, Yasuhiro Abe, Ryuji Kawano, Monika I. Konaklieva, Mart Reimund, Alan T. Remaley, Yoji Sato, Ken‑ichi Izutsu, Hiroyuki Saito. Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability Scientific Reports 2023, 13, 19396, DOI: 10.1038/s41598-023-46754-0

Yamamoto H, Elbadawy M, Tsunedomi R, Maeda N, Nagano H, Ishihara Y, Abugomaa A, Shiota Y, Yu TW, Liu Y, Nagashima Y, Kobayashi Y, Matsui R, Uomoto S, Kobayashi M, Yoshida T, Shibutani M, Kobayashi T, Inoue M, Higashinaka M, Fukushima R, Azakami D, Uchide T, Shinohara Y, Yamawaki H, Kaneda M, Usui T, Sasaki K. Novel organoid-based exploration reveals the role of LMTK3/FADS2 signaling in metastatic breast cancer progression in felines and humans. Scientific Reports. 15: 45016. 2025.

Kanaya, A., Nabeta, R., Yu, T., Yamamoto, H., Liu, YS., Abugomaa, A., Elbadawy, M., Shimoda, K., Usui, T., Uchide, T. Generation and characterization of feline colorectal adenocarcinoma organoids as a preclinical model. JOURNAL OF VETERINARY MEDICAL SCIENCE (J Vet Med Sci.), 87.7, 8752-762, 2025

Ueda, T., Chikaoka, Y., Matsuoka, S., Miyashita, N., Ohshima, K., Habuka, Y., Naoi, W., Iwama, E., Simon, P., and Naoi, K., Effect of SBPBF4 addition in Acetonitrile- and Linear Carbonate-based Electrolytes: Improving Voltage Stability and Reducing Gas Evolution in Supercapacitors, Electrochimica Acta (Electrochim. Acta), Accepted on 1st April 2025, Available online on 3rd April 2025, DOI: 10.1021/acsenergylett.5c00540