Event
Online【GIR Open Seminar】Dr. Mauro Chinappi / University of Rome Tor Vergata (Italy)
| Date | 2024.2.1 (16：00 - 17：00) |
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| Venue | |
| Speaker | Dr. Mauro Chinappi |
| Affiliation | University of Rome Tor Vergata (Italy) |
| Title | "Engineering nanopores to capture and analyze peptides via electroosmotic flow" ＜Abstract＞ Nanopores are powerful tools for single molecule sensing of biomolecules and nanoparticles. The signal associated to the molecule to be analyzed strongly depends on its interaction with the narrower section of the pore (constriction) that may be modified to improve the sensing accuracy. Modification of the pore constriction have been also commonly used to induce an electroosmotic flow that is able to favour the capture of the molecules in the pore under a voltage bias. However, designing pore modifications able to increase both electroosmosis and sensing accuracy is challenging. In this seminar, I will review the main transport phenomena in nanopores and introduce our recent results on analysis of peptides via nanopore sensors. In particular, I’ll show that it is possible to achieve an intense electroosmotic flow without altering the pore constriction. This strategy provide much more flexibility in the pore design since electroosmosis can be controlled modifying the pore far from the constriction while the constriction can be ptimized to improve sensing accuracy. |
| Language | English |
| Intended for | Registration is required. |
| Co-Organized by | Institute of Global Innovation Research, "Life Science" Kawano Team Excellent Leader Development for Super Smart Society by New Industry Creation and Diversity |
| Contact | Institute of Global Innovation Research, Institute of Engineering Prof. Ryuji Kawano Email: rjkawano (at) cc.tuat.ac.jp |
| Remarks | ※On-line Seminar by Zoom |
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