【GIR Open Seminar】 Dr. Takeshi Harayama / Institut de Pharmacologie Moléculaire et Cellulaire – CNRS, Université Côte d’Azur (France) | Institute of Global Innovation Research (Tokyo University of Agriculture and Technology)

【GIR Open Seminar】 Dr. Takeshi Harayama / Institut de Pharmacologie Moléculaire et Cellulaire – CNRS, Université Côte d’Azur (France)

Date	2023.11.16 (16：30 - 17：30)
Venue	Lecture Room L0811, 1st. Fl., Building 8, Koganei Campus, TUAT
Speaker	Dr. Takeshi Harayama
Affiliation	Institut de Pharmacologie Moléculaire et Cellulaire - CNRS, Université Côte d'Azur (France)
Title	"From Head to Toe : Biological significances of lipid head group and acylchain combinations" ＜Abstract＞ Changes in lipid profiles are seen in multiple diseases, but a basic understanding about how lipid structures affect biological functions remains to be established. It is known that lipids have distinct acyl-chain profiles depending on their head groups, and therefore we are investigating how this combination of head group and acyl-chains is acquired, and for which purpose. For this, we obtained lipidomics profiles from dozens of mutant cells with altered lipid metabolism, and found complex rules that delineate lipid class-specific acyl-chain regulation. In my presentation, I will present our recent results about the co-regulation of acyl-chains between sphingolipids and phosphatidylserine, as well as the generation of acyl-chain biases in phosphatidylinositol.
Language	English
Intended for	Everyone is welcome to join.
Co-Organized by	Institute of Global Innovation Research, "Life Science" Kawano Team Excellent Leader Development for Super Smart Society by New Industry Creation and Diversity
Contact	Institute of Global Innovation Research, Institute of Engineering Assoc. Prof. Hiroshi Tsugawa Email: htsugawa(at) go.tuat.ac.jp