| Date | 2023.7.20 (16：00 - 17：00) |
|---|---|
| Venue | |
| Speaker | Dr. Takanari Inoue |
| Affiliation | Johns Hopkins University (U.S.A.) |
| Title | "Constructing and deconstructing RNA granules" ＜Abstract＞ The function of proteins and nucleic acids within a cell is determined by their primary sequence. Recent work, however, has shown that within living cells the role of many proteins and RNA molecules can be influenced by the physical state in which the molecule is found. More specifically, proteins and RNA molecules can undergo condensation to form non-membrane-bound structures collectively known as RNA granules. Based on chemical and optical genetics schemes, our group recently developed two distinct molecular techniques to either construct or deconstruct RNA granules including stress granules and pathological condensates related to neurodegenerative diseases. I will introduce how we designed, developed and implemented such techniques, and share biological insights obtained from the unique probing of these redefined subcellular organizations. |
| Language | English |
| Intended for | Registration is required. |
| Co-Organized by | Institute of Global Innovation Research, "LIFE SCIENCE" Kawano Team Excellent Leader Development for Super Smart Society by New Industry Creation and Diversity |
| Contact | Institute of Global Innovation Research, Institute of Engineering Prof. Ryuji Kawano Email: rjkawano(at)cc.tuat.ac.jp |
| Remarks | ※For the registration, please contact Prof. Kawano (e-mail: rjkawano@cc.tuat.ac.jp) |
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