Event
【GIR Open Seminar】Dr. Antonio Di Pietro / University of Cordoba (Spain)
| Date | 2022.11.10 (16：30 - 17：00) |
|---|---|
| Venue |
Room 2-401, Building 2, Fuchu Campus, TUAT Meeting ID:770 525 2987 Passcode:263812 |
| Google Classroom Code | bx4cee6 |
| Speaker | Dr. Antonio Di Pietro |
| Affiliation | University of Cordoba (Spain) |
| Title | "ADAPTATION STRATEGIES IN A CLONALLY EVOLVING FUNGAL PATHOGEN" ＜Abstract＞ A hallmark of fungal pathogens is the ability to dynamically re-shape their growth and metabolism during the interaction with the host. The infection process is driven by rapid responses in cell signaling and gene expression as well as by long-term changes in genome structure. Understanding the molecular basis of this remarkable cellular and genetic plasticity is critical to control fungal disease. Our lab studies host adaptation in Fusarium oxysporum, a soil-inhabiting fungus that causes vascular wilt in more than a hundred different crops and life-threatening infections in humans. Strikingly, a single isolate of F. oxysporum can kill tomato plants, immunodepressed mice and the insect host Galleria. We use a combination of experimental evolution and reverse genetics to follow the dynamics of host adaptation and to identify the underlying molecular mechanisms, with a particular focus on MAPK-regulated invasive growth and on the role of transposons in the generation of genetic variation. |
| Language | English |
| Intended for | Everyone is welcome to join. |
| Co-Organized by | Institute of Global Innovation Research, “FOOD” Fukuhara Team Excellent Leader Development for Super Smart Society by New Industry Creation and Diversity |
| Contact | Institute of Global Innovation Research, Institute of Agriculture Prof. Tsutomu Arie Email: arie(at) cc.tuat.ac.jp |
| Remarks | This seminar will be held both face-to-face and online concurrently. |
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