| Date | 2022.2.16 (10：00 - 11：00) |
|---|---|
| Venue | |
| Google Classroom Code | bqvxypj |
| Speaker | Dr. Hisashi Koiwa |
| Affiliation | Texas A&M University (U.S.A.) |
| Title | Google classroom is now available. 1. Go to https://classroom.google.com and sign in. 2. At the upper right, click 「+」 and click 「join」. 3. Enter the class code bqvxypj --------------------------------------------------------------------------- ※On-line Seminar via Zoom and Google Classroom. Join the Zoom Meeting https://tuat-jp.zoom.us/j/81526572481?pwd=MGZrMXNjcWhoS0V5UHR6OUlzSnhUdz09 Meeting ID: 815 2657 2481 Pass Code: 473222 --------------------------------------------------------------------------------------------------------------------- ◆Dr. Hisashi Koiwa (Professor, Department of Horticultural Sciences, Texas A&M University, U.S.A.) ◆Title: ER and post-Golgi protein quality control of KORRIGAN1 in Arabidopsis thaliana Upon synthesis, proteins undergo a series of quality control system to produce, mature functional molecules. In endoplasmic reticulum (ER) of eukaryotes, N-glycosylation of the nascent peptides is a protein modification important to assist ER protein quality control consists of chaperon-assisted protein folding as well as ER-associated protein degradation (ERAD). On the other hand, little is known about their roles that operate downstream of ER. We previously showed that the plant N-glycans are essential for establishing osmotic stress tolerance in root growth, and KORRIGAN1 (KOR1), a component of cellulose biosynthesis machinery is one of the major targets. Quality control of KOR1 occurs not only at the ER but also after KOR1 exits ER and reaches plasmamembrane, where compromised proteins are removed and transported to the tonoplasts. We use inhibitor-based genetic screening and fluorescent imaging approach to understand and visualize dynamics of KOR1 in the cell and how it responds to environmental stress. |
| Language | English |
| Intended for | Everyone is welcome to join. |
| Co-Organized by | Institute of Global Innovation Research "FOOD", Fukuhara Team Excellent Leader Development for Super Smart Society by New Industry Creation and Diversity |
| Contact | Institute of Global Innovation Research, Institute of Agriculture Prof. Toshiyuki Fukuhara e-mail: fuku(at) cc.tuat.ac.jp |
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