The purpose of this research unit is to establish an international research center for material-cycle-based manufacturing that efficiently and sustainably recovers, circulates, and utilizes the abundant energy, mineral, and unused organic resources in the ocean. In order to solve global-scale issues such as energy, resources, and food, it is essential to develop manufacturing and energy strategies based on an understanding of material cycles from a global perspective that includes both terrestrial and marine areas. Therefore, we will promote an integrated resource-utilizing manufacturing strategy based on blue transformation that makes the most of the advantageous geographical features of Japan as a maritime nation. Specifically, in addition to the creation of new materials and alternative materials to plastics by utilizing the abundant biodiversity of the ocean as blue mineral resources, new energy development using blue carbon and carbon sequestration technology in the sea area will be developed. Furthermore, in order to conserve and sustainably utilize useful organisms with high productivity, research on material cycles, including the food chain, will be developed.